RS1295685 Unknown gene
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What This Variant Does
"rs1295685 and rs20541 were significantly associated with elevated IgE levels in pooled analyses. rs2..."
GWAS Studies (11)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Psoriasis | A | OR: 0.14 | 2E-33 | PubMed |
| Asthma | G | β: 0.082 | 2E-24 | PubMed |
| Allergic disease (asthma, hay fever or eczema) | A | OR: 1.07 | 3E-19 | PubMed |
| Atopic dermatitis | G | OR: 0.23 | 2E-17 | PubMed |
| Pediatric asthma | G | β: 0.097 | 2E-16 | PubMed |
| Psoriasis or type 2 diabetes (trans-disease meta-analysis)(opposite effect) | G | OR: 1.1 | 2E-14 | PubMed |
| Psoriasis vulgaris | G | OR: 1.22 | 3E-14 | PubMed |
| Psoriasis or type 2 diabetes (trans-disease meta-analysis) | A | OR: 1.1 | 5E-13 | PubMed |
| Eczema | — | — | 6E-13 | PubMed |
| Psoriasis | G | OR: 1.18 | 3E-10 | PubMed |
| Asthma (childhood onset) | A | OR: 1.16 | 2E-9 | PubMed |