RS12413578 Unknown gene
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What This Variant Does
"One of 42 more SNPs associated with rheumatoid arthritis based on a meta-analysis of 30,000 patients..."
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Asthma | C | OR: 1.17 | 9E-47 | PubMed |
| Asthma | C | OR: 1.16 | 8E-41 | PubMed |
| Asthma (childhood onset) | — | OR: 1.18 | 9E-41 | PubMed |
| Allergic disease (asthma, hay fever or eczema) | C | OR: 1.1 | 1E-27 | PubMed |
| Nonatopic asthma | — | — | 1E-27 | PubMed |
| Asthma (adult onset) | — | — | 5E-26 | PubMed |
| Asthma | — | OR: 0.85 | 1E-24 | PubMed |
| Atopic asthma | — | — | 3E-23 | PubMed |
| Asthma (childhood onset) | — | — | 4E-21 | PubMed |
| Medication use (glucocorticoids) | T | OR: 0.17 | 5E-21 | PubMed |
| Eosinophil count | T | β: 0.033 | 3E-17 | PubMed |
| Eosinophil percentage of white cells | T | β: 0.033 | 1E-16 | PubMed |
| Asthma | — | — | 1E-15 | PubMed |
| Eosinophil count | T | β: 0.047 | 8E-13 | PubMed |
| Asthma | — | OR: 1.12 | 8E-12 | PubMed |
| Lung function (FEV1/FVC) | T | OR: 6.6 | 4E-11 | PubMed |
| FEV1/FVC ratio | — | — | 6E-11 | PubMed |
| Allergic disease (asthma, hay fever or eczema) | — | OR: 1.11 | 5E-10 | PubMed |
| Forced expiratory volume in 1 second (FEV1) | — | — | 4E-9 | PubMed |
| Rheumatoid arthritis | C | OR: 1.2 | 5E-8 | PubMed |