RS12248560 CYP2C19

Drug Response Chr 10:94761899 snv intron variant

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What This Variant Does

"rs12248560(T) defines the CYP2C19*17 allele, an ultra fast metabolizer phenotype of the CYP2C19 gene...

Associated Conditions

CYP2C19: increased function

Clopidogrel response

CYP2C19: increased function

Clopidogrel response

Medication Interactions

Clopidogrel efficacy strong

CYP2C19*17 — ultra-rapid metaboliser, enhanced effect

Population Frequencies

1kG AFR

23.5%

1kG ALL

84.7%

1kG AMR

88%

1kG EAS

1.5%

1kG EUR

77.6%

1kG SAS

86.4%

Other Variants in CYP2C19