RS11642015 Unknown gene
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What This Variant Does
"Polymorphisms in FTO and near TMEM18 associate with type 2 diabetes and predispose to younger age at diagnosis of diabetes"
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Body mass index | C | β: 0.074 | 4E-315 | PubMed |
| Body mass index | T | β: 0.074 | 9E-290 | PubMed |
| Body mass index | — | — | 7E-217 | PubMed |
| Body mass index | T | β: 0.076 | 2E-213 | PubMed |
| Arm fat percentage left (UKB data field 23123) | T | β: 0.041 | 2E-170 | PubMed |
| Waist circumference | C | β: 0.057 | 5E-167 | PubMed |
| Body fat percentage | T | β: 0.041 | 7E-165 | PubMed |
| Arm fat percentage right (UKB data field 23119) | T | β: 0.04 | 1E-163 | PubMed |
| Whole body fat mass (UKB data field 23100) | T | β: 0.065 | 3E-163 | PubMed |
| Obesity (PheCode 278.1) | C | OR: 0.14 | 5E-162 | PubMed |
| Metabolic biomarkers (multivariate analysis) | T | — | 2E-157 | PubMed |
| Body fat percentage (UKB data field 23099) | T | β: 0.036 | 5E-135 | PubMed |
| BMI and adiposity (confirmatory factor analysis Factor 7) | — | — | 2E-133 | PubMed |
| Leg fat percentage left (UKB data field 23115) | T | β: 0.029 | 9E-128 | PubMed |
| Body fat percentage | C | β: 0.041 | 1E-112 | PubMed |
| Type 2 diabetes (PheCode 250.2) | C | OR: 0.12 | 2E-95 | PubMed |
| Body mass index | T | β: 0.077 | 2E-85 | PubMed |
| Body mass index | T | β: 0.081 | 2E-81 | PubMed |
| Body mass index variance | — | — | 2E-73 | PubMed |
| Menarche (age at onset) | — | — | 1E-57 | PubMed |