RS113298164 LIPC
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What This Variant Does
"[OMIM:?]
Associated Conditions
Hyperlipidemia due to hepatic triglyceride lipase deficiency
High density lipoprotein cholesterol level quantitative trait locus 12
Type 1 diabetes mellitus 2
Type 2 diabetes mellitus
Hyperlipidemia due to hepatic triglyceride lipase deficiency
High density lipoprotein cholesterol level quantitative trait locus 12
Type 1 diabetes mellitus 2
Type 2 diabetes mellitus
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Triglyceride levels in large HDL | C | OR: 0.82 | 1E-75 | PubMed |
| Free cholesterol to total lipids ratio in small HDL | C | OR: 0.75 | 7E-64 | PubMed |
| 1-palmitoyl-2-docosahexaenoyl-GPE (16:0/22:6) levels | T | OR: 1.19 | 1E-61 | PubMed |
| Triglyceride levels in very large HDL | C | OR: 0.75 | 4E-61 | PubMed |
| Apolipoprotein A1 levels | — | OR: 0.37 | 2E-59 | PubMed |
| Triglyceride levels in IDL | C | OR: 0.73 | 5E-57 | PubMed |
| HDL cholesterol levels | — | OR: 0.34 | 1E-54 | PubMed |
| Cholesteryl esters to total lipids ratio in small HDL | C | OR: 0.71 | 4E-54 | PubMed |
| Phospholipids to total lipids ratio in large LDL | C | OR: 0.7 | 8E-50 | PubMed |
| Triglyceride levels in large LDL | C | OR: 0.68 | 4E-49 | PubMed |
| Cholesterol to total lipids ratio in very large HDL | C | OR: 0.65 | 2E-47 | PubMed |
| 1-palmitoyl-2-arachidonoyl-GPE (16:0/20:4) levels | T | OR: 1.02 | 4E-42 | PubMed |
| Triglyceride levels in very small VLDL | C | OR: 0.62 | 5E-42 | PubMed |
| Phospholipid levels in very small VLDL | C | OR: 0.62 | 1E-41 | PubMed |
| Triglyceride levels in LDL | C | OR: 0.61 | 5E-40 | PubMed |
| Apolipoprotein A levels (UKB data field 30630) | T | OR: 0.27 | 7E-40 | PubMed |
| Triglycerides to total lipids ratio in medium LDL | C | OR: 0.61 | 2E-39 | PubMed |
| Total lipid levels in very small VLDL | C | OR: 0.6 | 2E-38 | PubMed |
| Concentration of very large HDL particles | C | OR: 0.55 | 3E-38 | PubMed |
| Average diameter for HDL particles | C | OR: 0.52 | 2E-36 | PubMed |
Other Variants in LIPC