RS10774624 Unknown gene
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What This Variant Does
"One of 42 more SNPs associated with rheumatoid arthritis based on a meta-analysis of 30,000 patients..."
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| platelet count (mean, inv-norm transformed) | G | OR: 0.12 | 1E-323 | PubMed |
| eosinophil (absolute count, mean, inv-norm transformed) | G | OR: 0.13 | 1E-323 | PubMed |
| Eosinophil count | — | — | 1E-300 | PubMed |
| KLRK1 protein levels | A | β: 0.071 | 1E-39 | PubMed |
| KIR2DL2 protein levels | A | β: 0.058 | 1E-32 | PubMed |
| Kynurenine levels | A | OR: 0.11 | 1E-27 | PubMed |
| HNRNPUL1 protein levels | A | β: 0.059 | 1E-23 | PubMed |
| Vitiligo | G | OR: 1.27 | 6E-23 | PubMed |
| UBE2L6 protein levels | A | β: 0.058 | 8E-23 | PubMed |
| eosinophil (absolute count, minimum, inv-norm transformed) | G | β: 0.068 | 1E-19 | PubMed |
| TYMP protein levels | A | β: 0.053 | 2E-19 | PubMed |
| Systolic blood pressure | G | OR: 0.48 | 3E-19 | PubMed |
| C-X-C motif chemokine 16 levels | A | β: 0.072 | 6E-19 | PubMed |
| Interleukin-27 levels | A | β: 0.074 | 8E-19 | PubMed |
| Atherosclerosis of the extremities (PheCode 440.2) | G | β: 0.099 | 2E-17 | PubMed |
| Total cholesterol levels in HDL | A | β: 0.033 | 2E-15 | PubMed |
| NAGK protein levels | A | β: 0.045 | 6E-15 | PubMed |
| HMCN2 protein levels | A | β: 0.039 | 7E-15 | PubMed |
| JAM2 protein levels | A | β: 0.04 | 2E-14 | PubMed |
| Heart failure | G | β: 0.034 | 2E-14 | PubMed |