RS10741657 Unknown gene
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What This Variant Does
"rs10741657, located near the cytochrome P450, family 2, subfamily R, polypeptide 1 CYP2R1 gene on ch..."
Related Biomarkers
Vitamin D (25-OH)
monitor
moderate
Related Supplements
Vitamin D3 may support
moderate
CYP2R1 — reduced hydroxylation, may benefit from higher doses
GWAS Studies (6)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Vitamin D levels | A | β: 0.031 | 2E-46 | PubMed |
| Vitamin D levels (dietary vitamin D intake interaction) | A | — | 2E-38 | PubMed |
| Vitamin D insufficiency | — | — | 3E-20 | PubMed |
| Serum 25-Hydroxyvitamin D levels | A | OR: 2.1 | 3E-11 | PubMed |
| Serum 25-Hydroxyvitamin D levels | A | — | 2E-6 | PubMed |
| Sphingomyelin (d18:0/18:0, d19:0/17:0) levels in elite athletes | — | OR: 0.31 | 6E-6 | PubMed |