RS1064725 Unknown gene
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What This Variant Does
"Apolipoprotein E gene polymorphism modifies fasting total cholesterol concentrations in response to replacement of dietary saturated with monounsaturated fatty acids in adults at moderate cardiovascular disease risk."
GWAS Studies (16)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| APOC1 protein levels | G | OR: 0.15 | 4E-25 | PubMed |
| Triglyceride to HDL cholesterol ratio | T | β: 0.081 | 6E-23 | PubMed |
| Triglyceride levels | G | β: 0.061 | 3E-22 | PubMed |
| C-reactive protein levels (MTAG) | T | β: 0.043 | 2E-17 | PubMed |
| Triglyceride to HDL cholesterol ratio | T | β: 0.084 | 3E-17 | PubMed |
| C-reactive protein levels | G | β: 0.047 | 4E-14 | PubMed |
| Triglyceride levels (MTAG) | T | β: 0.046 | 3E-13 | PubMed |
| Monounsaturated fatty acids to total fatty acids percentage | G | — | 4E-11 | PubMed |
| Polyunsaturated fatty acids to monounsaturated fatty acids ratio | G | — | 6E-11 | PubMed |
| Monounsaturated fatty acid levels | G | — | 4E-10 | PubMed |
| Omega-6 fatty acids to total fatty acids percentage | G | — | 7E-10 | PubMed |
| Monounsaturated fatty acids to total fatty acids percentage | G | — | 2E-9 | PubMed |
| Triglyceride to HDL cholesterol ratio | T | β: 0.055 | 4E-9 | PubMed |
| Polyunsaturated fatty acids to total fatty acids percentage | G | — | 7E-9 | PubMed |
| Omega-6 fatty acids to total fatty acids percentage | G | — | 2E-8 | PubMed |
| Polyunsaturated fatty acids to monounsaturated fatty acids ratio | G | — | 2E-8 | PubMed |