RS1057868 Unknown gene
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What This Variant Does
"rs1057868, also known as A503V, is a relatively common variant defining the POR*28 allele of the P45...
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Coffee consumption (cups per day) | C | β: 0.029 | 5E-36 | PubMed |
| Coffee consumption | T | β: 0.02 | 1E-33 | PubMed |
| Creatinine levels in bottom 99% of individuals by creatinine levels | — | OR: 0.29 | 3E-28 | PubMed |
| Serum creatinine levels | T | β: 0.018 | 1E-26 | PubMed |
| Creatinine levels (UKB data field 30700) | T | β: 0.019 | 2E-26 | PubMed |
| Creatinine levels | T | β: 0.013 | 1E-25 | PubMed |
| Estimated glomerular filtration rate (creatinine) | T | β: 0.024 | 2E-25 | PubMed |
| Triglyceride levels | T | β: 0.016 | 2E-23 | PubMed |
| Bitter non-alcoholic beverage consumption | T | β: 0.018 | 4E-23 | PubMed |
| Caffeine consumption from coffee | C | β: 0.024 | 6E-22 | PubMed |
| Cholesteryl Esters to Total Lipids in Medium HDL percentage | T | β: 0.02 | 1E-19 | PubMed |
| Estimated glomerular filtration rate based on creatinine and cystatin C in bottom 99% of individuals by creatinine levels | — | OR: 2.4 | 5E-19 | PubMed |
| Cholesterol to Total Lipids in Medium HDL percentage | T | β: 0.02 | 5E-17 | PubMed |
| Estimated glomerular filtration rate (creatinine, cystatin c) | T | β: 0.019 | 6E-17 | PubMed |
| Cholesteryl Esters to Total Lipids in Large HDL percentage | T | β: 0.02 | 1E-16 | PubMed |
| NADPH--cytochrome P450 reductase levels | T | OR: 0.2 | 2E-16 | PubMed |
| Triglycerides in very small VLDL | T | β: 0.02 | 3E-16 | PubMed |
| Platelet count | T | β: 0.013 | 1E-15 | PubMed |
| Cholesterol to Total Lipids in Small HDL percentage | T | β: 0.02 | 1E-15 | PubMed |
| Cholesteryl Esters to Total Lipids in Small HDL percentage | T | β: 0.02 | 3E-15 | PubMed |