RS10488631 Unknown gene
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What This Variant Does
"rs10488631, a SNP located 3' of the IRF5 gene, has been reported as a possibly causative SNP for sys..."
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Systemic lupus erythematosus (MTAG) | T | OR: 0.4 | 2E-143 | PubMed |
| Systemic lupus erythematosus | C | OR: 1.92 | 9E-110 | PubMed |
| Primary biliary cholangitis | C | OR: 1.59 | 5E-23 | PubMed |
| Systemic lupus erythematosus | C | OR: 1.92 | 7E-18 | PubMed |
| Systemic lupus erythematosus | C | OR: 1.83 | 2E-13 | PubMed |
| Systemic sclerosis | C | OR: 1.5 | 2E-13 | PubMed |
| Primary biliary cirrhosis | C | OR: 1.56 | 3E-12 | PubMed |
| Systemic lupus erythematosus | C | — | 2E-11 | PubMed |
| Rheumatoid arthritis | C | OR: 1.21 | 4E-11 | PubMed |
| Systemic sclerosis | — | OR: 1.5 | 2E-10 | PubMed |
| Primary biliary cholangitis | C | OR: 1.63 | 3E-10 | PubMed |
| Limited cutaneous systemic scleroderma | — | — | 3E-10 | PubMed |
| Diffuse cutaneous systemic sclerosis | — | — | 1E-9 | PubMed |
| Systemic sclerosis | — | OR: 1.52 | 2E-7 | PubMed |
| Primary biliary cholangitis | G | OR: 1.52 | 2E-7 | PubMed |
| Systemic sclerosis (anti-topoisomerase-positive) | — | — | 4E-7 | PubMed |
| Systemic sclerosis | C | OR: 1.35 | 4E-7 | PubMed |
| Systemic sclerosis | C | OR: 1.63 | 6E-7 | PubMed |
| Systemic sclerosis (anti-centromere-positive) | — | — | 9E-7 | PubMed |
| Limited cutaneous systemic scleroderma | — | — | 9E-7 | PubMed |