RS10246939 TAS2R38

Drug Response Chr 7:141972803 snv missense variant

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What This Variant Does

"rs10246939 is one of three SNPs that form the main haplotypes behind the ability to perceive as bitt...

Associated Conditions

Phenylthiocarbamide tasting

GWAS Studies (5)

Trait	Risk Allele	OR / Beta	P-value	Study
Bitter taste perception	—	OR: 0.97	3E-199	PubMed
Bitter taste perception	—	OR: 0.39	2E-62	PubMed
Salty food liking	C	β: 0.028	1E-15	PubMed
F-wine liking (derived food-liking factor)	C	β: 0.023	7E-11	PubMed
Smoking initiation	C	β: 0.005	4E-10	PubMed

Population Frequencies

gnomAD ALL

45.5%

1kG AFR

47.7%

1kG ALL

52.1%

1kG AMR

31.3%

1kG EAS

32.3%

1kG EUR

53.9%

1kG SAS

63.8%

Other Variants in TAS2R38