RS10119 Unknown gene
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What This Variant Does
"Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Family history of Alzheimer's disease | — | OR: 1.44 | 1E-307 | PubMed |
| Alzheimer's disease | A | — | 2E-161 | PubMed |
| Alzheimer's disease or family history of Alzheimer's disease | A | — | 4E-131 | PubMed |
| Memory decline | — | β: 0.018 | 1E-60 | PubMed |
| Baseline memory | — | OR: 0.15 | 3E-59 | PubMed |
| Memory decline | — | β: 0.016 | 3E-58 | PubMed |
| Late-onset Alzheimer's disease | — | OR: 2.73 | 2E-57 | PubMed |
| Baseline memory | — | OR: 0.14 | 5E-56 | PubMed |
| Memory decline | — | β: 0.017 | 1E-50 | PubMed |
| Memory decline | — | β: 0.017 | 2E-48 | PubMed |
| Baseline memory | — | OR: 0.14 | 6E-44 | PubMed |
| Baseline memory | — | OR: 0.13 | 9E-43 | PubMed |
| Memory decline in impaired cognition | — | β: 0.029 | 3E-38 | PubMed |
| Baseline memory in impaired cognition | — | OR: 0.21 | 1E-30 | PubMed |
| Baseline memory in impaired cognition | — | OR: 0.16 | 2E-25 | PubMed |
| Multi-trait sum score | — | — | 3E-22 | PubMed |
| Vascular dementia | G | OR: 0.33 | 1E-17 | PubMed |
| Multi-trait sum score | — | — | 4E-14 | PubMed |
| Memory decline in normal cognition | — | β: 0.008 | 4E-14 | PubMed |
| Memory decline in normal cognition | — | β: 0.008 | 4E-14 | PubMed |