RS1004467 Unknown gene
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What This Variant Does
"23andMe blog blood pressure Common variants in or near FGF5, CYP17A1 and MTHFR genes are associated ..."
GWAS Studies (18)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Systolic blood pressure | A | OR: 0.83 | 3E-41 | PubMed |
| Pulse pressure | A | OR: 0.53 | 1E-37 | PubMed |
| Pulse pressure | A | OR: 0.5 | 3E-19 | PubMed |
| Diastolic blood pressure | A | OR: 0.32 | 6E-17 | PubMed |
| Hypertension | — | β: 0.089 | 4E-16 | PubMed |
| Mean arterial pressure | C | OR: 0.49 | 2E-11 | PubMed |
| Systolic blood pressure | A | OR: 0.66 | 6E-11 | PubMed |
| Systolic blood pressure | A | OR: 1.05 | 1E-10 | PubMed |
| Systolic blood pressure | A | OR: 0.51 | 1E-10 | PubMed |
| Pulse pressure | A | OR: 0.34 | 4E-10 | PubMed |
| Hypertension | A | β: 0.082 | 5E-9 | PubMed |
| Systolic blood pressure x depressive symptoms interaction (2df test) | — | — | 1E-8 | PubMed |
| Neuroticism | G | β: 0.017 | 1E-8 | PubMed |
| Depressive symptoms | G | β: 0.011 | 2E-8 | PubMed |
| Myocardial infarction | A | OR: 1.08 | 8E-8 | PubMed |
| Mean arterial pressure | A | OR: 0.28 | 5E-7 | PubMed |
| Psycho-cardiometabolic multimorbidity (multivariate analysis) | — | β: 0.023 | 5E-6 | PubMed |
| Systolic blood pressure | A | OR: 1.15 | 6E-6 | PubMed |