ZNF644 Chromosome 1

Zinc finger protein 644

3 variants 3 Health Risk

Upload your DNA to see your personal genotypes for variants in ZNF644.

What This Gene Does

The protein encoded by this gene is a zinc finger transcription factor that may play a role in eye development. Defects in this gene have been associated with high myopia. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

Gene Info

Gene Group

Zinc fingers C2H2-type

Locus Type

gene with protein product

Location

1p22.2

Ensembl

ENSG00000122482

Associated Conditions (2)

Myopia 21

autosomal dominant

Key Variants

RS146936371

Pathogenic

Myopia 21, autosomal dominant, Myopia 21

Health Risk

RS387907109

Pathogenic

Myopia 21, autosomal dominant, Myopia 21

Health Risk

RS587776903

Pathogenic

Myopia 21, autosomal dominant, Myopia 21

Health Risk

All Variants (3)

RSID	Category	Clinical Significance	Conditions
RS146936371	Health Risk	Pathogenic	Myopia 21, autosomal dominant, Myopia 21
RS387907109	Health Risk	Pathogenic	Myopia 21, autosomal dominant, Myopia 21
RS587776903	Health Risk	Pathogenic	Myopia 21, autosomal dominant, Myopia 21