TNRC6A Chromosome 16
Trinucleotide repeat containing adaptor 6A
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What This Gene Does
This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. [provided by RefSeq, Jul 2008]
Gene Info
Gene Group
TNRC6 adaptor family
Locus Type
gene with protein product
Location
16p12.1
Ensembl
ENSG00000090905
Key Variants
All Variants (3)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS143822830 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS372228558 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS573474554 | Health Risk | Conflicting classifications of pathogenicity | — |