TGS1 Chromosome 8
Trimethylguanosine synthase 1
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What This Gene Does
Enables RNA cap trimethylguanosine synthase activity. Involved in 7-methylguanosine cap hypermethylation. Located in cytosol and nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
"7BS DNA/RNA methyltransferases|DNA/RNA methyltransferases"
Locus Type
gene with protein product
Location
8q12.1
Ensembl
ENSG00000137574
Key Variants
All Variants (2)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS61754978 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS61754979 | Health Risk | Conflicting classifications of pathogenicity | — |