SUGCT Chromosome 7
Succinyl-CoA:glutarate-CoA transferase
Upload your DNA to see your personal genotypes for variants in SUGCT.
What This Gene Does
This gene encodes a protein that is similar to members of the CaiB/baiF CoA-transferase protein family. Mutations in this gene are associated with glutaric aciduria type III. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]
Gene Info
Gene Group
Flavoproteins
Locus Type
gene with protein product
Location
7p14.1
Ensembl
ENSG00000175600
Associated Conditions (2)
Glutaryl-CoA oxidase deficiency
SUGCT-related disorder
Key Variants
RS137852860
Conflicting classifications of pathogenicity
Glutaryl-CoA oxidase deficiency, SUGCT-related disorder, Glutaryl-CoA oxidase deficiency
Health Risk
RS137852862
Conflicting classifications of pathogenicity
Glutaryl-CoA oxidase deficiency, Glutaryl-CoA oxidase deficiency
Health Risk
RS138102615
Conflicting classifications of pathogenicity
SUGCT-related disorder, SUGCT-related disorder
Health Risk
RS147837552
Conflicting classifications of pathogenicity
Health Risk
RS193023834
Conflicting classifications of pathogenicity
Health Risk
RS370031397
Conflicting classifications of pathogenicity
Health Risk
RS752118948
Conflicting classifications of pathogenicity
Glutaryl-CoA oxidase deficiency, Glutaryl-CoA oxidase deficiency
Health Risk
RS759909394
Conflicting classifications of pathogenicity
Health Risk
RS2150734056
Likely pathogenic
Glutaryl-CoA oxidase deficiency, Glutaryl-CoA oxidase deficiency
Health Risk
RS137852861
Pathogenic
Glutaryl-CoA oxidase deficiency, Glutaryl-CoA oxidase deficiency
Health Risk
All Variants (10)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS137852860 | Health Risk | Conflicting classifications of pathogenicity | Glutaryl-CoA oxidase deficiency, SUGCT-related disorder, Glutaryl-CoA oxidase deficiency |
| RS137852862 | Health Risk | Conflicting classifications of pathogenicity | Glutaryl-CoA oxidase deficiency, Glutaryl-CoA oxidase deficiency |
| RS138102615 | Health Risk | Conflicting classifications of pathogenicity | SUGCT-related disorder, SUGCT-related disorder |
| RS147837552 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS193023834 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS370031397 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS752118948 | Health Risk | Conflicting classifications of pathogenicity | Glutaryl-CoA oxidase deficiency, Glutaryl-CoA oxidase deficiency |
| RS759909394 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS2150734056 | Health Risk | Likely pathogenic | Glutaryl-CoA oxidase deficiency, Glutaryl-CoA oxidase deficiency |
| RS137852861 | Health Risk | Pathogenic | Glutaryl-CoA oxidase deficiency, Glutaryl-CoA oxidase deficiency |