SLCO2A1 Chromosome 3
Solute carrier organic anion transporter family member 2A1
Upload your DNA to see your personal genotypes for variants in SLCO2A1.
What This Gene Does
This gene encodes a prostaglandin transporter that is a member of the 12-membrane-spanning superfamily of transporters. The encoded protein may be involved in mediating the uptake and clearance of prostaglandins in numerous tissues. [provided by RefSeq, Dec 2011]
Gene Info
Gene Group
Solute carrier organic anion transporter family
Locus Type
gene with protein product
Location
3q22.1-q22.2
Ensembl
ENSG00000174640
Associated Conditions (11)
Inborn genetic diseases
Hypertrophic osteoarthropathy
primary
autosomal recessive
2
Thymoma
SLCO2A1-related disorder
autosomal dominant
Pachydermoperiostosis syndrome
Hepatocellular carcinoma
Cervical cancer
Key Variants
RS138923414
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS140769111
Conflicting classifications of pathogenicity
Hypertrophic osteoarthropathy, primary, autosomal recessive
Health Risk
RS142480645
Conflicting classifications of pathogenicity
Hypertrophic osteoarthropathy, primary, autosomal recessive
Health Risk
RS149946676
Conflicting classifications of pathogenicity
Hypertrophic osteoarthropathy, primary, autosomal recessive
Health Risk
RS200364668
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS375938553
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS556819076
Conflicting classifications of pathogenicity
Inborn genetic diseases, SLCO2A1-related disorder, Inborn genetic diseases
Health Risk
RS566240756
Conflicting classifications of pathogenicity
Hypertrophic osteoarthropathy, primary, autosomal recessive
Health Risk
RS772212922
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS1085307096
Likely pathogenic
Hypertrophic osteoarthropathy, primary, autosomal recessive
Health Risk
RS1376989560
Likely pathogenic
Hypertrophic osteoarthropathy, primary, autosomal recessive
Health Risk
RS1576444504
Likely pathogenic
Hypertrophic osteoarthropathy, primary, autosomal recessive
Health Risk
All Variants (56)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS778081416 | Health Risk | Pathogenic | Hypertrophic osteoarthropathy, primary, autosomal recessive |
| RS892909504 | Health Risk | Pathogenic | Hypertrophic osteoarthropathy, primary, autosomal recessive |
| RS387907295 | Health Risk | Pathogenic/Likely pathogenic | Hypertrophic osteoarthropathy, primary, autosomal recessive |
| RS768030732 | Health Risk | Pathogenic/Likely pathogenic | Hypertrophic osteoarthropathy, primary, autosomal recessive |
| RS774038272 | Health Risk | Pathogenic/Likely pathogenic | Hypertrophic osteoarthropathy, primary, autosomal recessive |
| RS776813259 | Health Risk | Pathogenic/Likely pathogenic | Hypertrophic osteoarthropathy, primary, autosomal recessive |