SERPINA12 Chromosome 14

Serpin family A member 12

1 variant 1 Health Risk

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What This Gene Does

Enables molecular function inhibitor activity. Predicted to act upstream of or within negative regulation of gluconeogenesis; positive regulation of signal transduction; and regulation of lipid metabolic process. Predicted to be located in extracellular region and plasma membrane. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Jul 2025]

Gene Info

Gene Group

Serpin peptidase inhibitors

Locus Type

gene with protein product

Location

14q32.13

Ensembl

ENSG00000165953

Associated Conditions (2)

Hereditary palmoplantar keratoderma

Gamborg-Nielsen type