ROGDI Chromosome 16
Rogdi atypical leucine zipper
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What This Gene Does
Involved in brain development; neurogenesis; and odontogenesis of dentin-containing tooth. Located in nuclear envelope. Implicated in Kohlschutter-Tonz syndrome. [provided by Alliance of Genome Resources, Jul 2025]
Associated Conditions (4)
Amelocerebrohypohidrotic syndrome
ROGDI-related disorder
Inborn genetic diseases
Gastric cancer
Key Variants
RS142481526
Conflicting classifications of pathogenicity
Amelocerebrohypohidrotic syndrome, ROGDI-related disorder, Amelocerebrohypohidrotic syndrome
Health Risk
RS143000899
Conflicting classifications of pathogenicity
Amelocerebrohypohidrotic syndrome, Amelocerebrohypohidrotic syndrome
Health Risk
RS144581570
Conflicting classifications of pathogenicity
Amelocerebrohypohidrotic syndrome, Amelocerebrohypohidrotic syndrome
Health Risk
RS144866271
Conflicting classifications of pathogenicity
Amelocerebrohypohidrotic syndrome, ROGDI-related disorder, Amelocerebrohypohidrotic syndrome
Health Risk
RS145588848
Conflicting classifications of pathogenicity
Amelocerebrohypohidrotic syndrome, Amelocerebrohypohidrotic syndrome
Health Risk
RS148051351
Conflicting classifications of pathogenicity
Amelocerebrohypohidrotic syndrome, ROGDI-related disorder, Amelocerebrohypohidrotic syndrome
Health Risk
RS200558978
Conflicting classifications of pathogenicity
Amelocerebrohypohidrotic syndrome, Amelocerebrohypohidrotic syndrome
Health Risk
RS201213891
Conflicting classifications of pathogenicity
Amelocerebrohypohidrotic syndrome, Amelocerebrohypohidrotic syndrome
Health Risk
RS2082694697
Conflicting classifications of pathogenicity
Amelocerebrohypohidrotic syndrome, Inborn genetic diseases, Amelocerebrohypohidrotic syndrome
Health Risk
RS371432203
Conflicting classifications of pathogenicity
Amelocerebrohypohidrotic syndrome, Amelocerebrohypohidrotic syndrome
Health Risk
RS371783831
Conflicting classifications of pathogenicity
Amelocerebrohypohidrotic syndrome, Inborn genetic diseases, Amelocerebrohypohidrotic syndrome
Health Risk
RS372520122
Conflicting classifications of pathogenicity
Amelocerebrohypohidrotic syndrome, Amelocerebrohypohidrotic syndrome
Health Risk
All Variants (52)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS372097881 | Health Risk | Pathogenic/Likely pathogenic | Amelocerebrohypohidrotic syndrome, Amelocerebrohypohidrotic syndrome |
| RS786205124 | Health Risk | Pathogenic/Likely pathogenic | Amelocerebrohypohidrotic syndrome, Amelocerebrohypohidrotic syndrome, Amelocerebrohypohidrotic syndrome |