RANGRF Chromosome 17

RAN guanine nucleotide release factor

2 variants 2 Health Risk

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What This Gene Does

This gene encodes a protein that has been shown to function as a guanine nucleotide release factor in mouse and to regulate the expression and function of the Nav1.5 cardiac sodium channel in human. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]

Associated Conditions (1)

Cardiac arrhythmia

Key Variants

RS147679793

Conflicting classifications of pathogenicity

Cardiac arrhythmia, Cardiac arrhythmia

Health Risk

RS150856064

Conflicting classifications of pathogenicity

Cardiac arrhythmia, Cardiac arrhythmia

Health Risk

All Variants (2)

RSID	Category	Clinical Significance	Conditions
RS147679793	Health Risk	Conflicting classifications of pathogenicity	Cardiac arrhythmia, Cardiac arrhythmia
RS150856064	Health Risk	Conflicting classifications of pathogenicity	Cardiac arrhythmia, Cardiac arrhythmia