QRICH1 Chromosome 3
Glutamine rich 1
Upload your DNA to see your personal genotypes for variants in QRICH1.
What This Gene Does
Enables DNA binding activity. Involved in intracellular signal transduction; positive regulation of DNA-templated transcription; and positive regulation of apoptotic process. Located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
Caspase recruitment domain containing
Locus Type
gene with protein product
Location
3p21.31
Ensembl
ENSG00000198218
Associated Conditions (5)
Ververi-Brady syndrome
Inborn genetic diseases
Ververi-Brady syndrome 1
Intellectual disability
Mild intellectual disability
Key Variants
RS2093408453
Conflicting classifications of pathogenicity
Ververi-Brady syndrome, Ververi-Brady syndrome
Health Risk
RS2106802170
Conflicting classifications of pathogenicity
Ververi-Brady syndrome, Ververi-Brady syndrome
Health Risk
RS2106903188
Conflicting classifications of pathogenicity
Ververi-Brady syndrome, Ververi-Brady syndrome
Health Risk
RS757870894
Conflicting classifications of pathogenicity
Inborn genetic diseases, Ververi-Brady syndrome 1, Inborn genetic diseases
Health Risk
RS1559920341
Likely pathogenic
Ververi-Brady syndrome, Ververi-Brady syndrome
Health Risk
RS2093229974
Likely pathogenic
Ververi-Brady syndrome, Ververi-Brady syndrome
Health Risk
RS2093252866
Likely pathogenic
Ververi-Brady syndrome, Ververi-Brady syndrome
Health Risk
RS2106813640
Likely pathogenic
Ververi-Brady syndrome, Ververi-Brady syndrome
Health Risk
RS2106854800
Likely pathogenic
Ververi-Brady syndrome, Ververi-Brady syndrome
Health Risk
RS2106855069
Likely pathogenic
Ververi-Brady syndrome, Ververi-Brady syndrome
Health Risk
RS2106862871
Likely pathogenic
Ververi-Brady syndrome, Ververi-Brady syndrome
Health Risk
RS2106862882
Likely pathogenic
Ververi-Brady syndrome, Inborn genetic diseases, Ververi-Brady syndrome
Health Risk
All Variants (55)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS2471710380 | Health Risk | Pathogenic | — |
| RS2471766903 | Health Risk | Pathogenic | Inborn genetic diseases, Inborn genetic diseases |
| RS746059690 | Health Risk | Pathogenic | Ververi-Brady syndrome, Ververi-Brady syndrome |
| RS763953500 | Health Risk | Pathogenic | Ververi-Brady syndrome, Ververi-Brady syndrome |
| RS2106904870 | Health Risk | Pathogenic/Likely pathogenic | Ververi-Brady syndrome, Ververi-Brady syndrome |