PRAMEF2 Chromosome 1
PRAME family member 2
Upload your DNA to see your personal genotypes for variants in PRAMEF2.
What This Gene Does
Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul2-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
PRAME family
Locus Type
gene with protein product
Location
1p36.21
Ensembl
ENSG00000120952
Key Variants
All Variants (4)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS200248611 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS200536956 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS201917301 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS559620534 | Health Risk | Conflicting classifications of pathogenicity | — |