NLGN1 Chromosome 3
Neuroligin 1
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What This Gene Does
This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. [provided by RefSeq, Jul 2008]
Gene Info
Gene Group
Neuroligins
Locus Type
gene with protein product
Location
3q26.31
Ensembl
ENSG00000169760
Associated Conditions (4)
Inborn genetic diseases
Autism
susceptibility to
20
Key Variants
RS749776633
Conflicting classifications of pathogenicity
Inborn genetic diseases, Autism, susceptibility to
Health Risk
RS1750373491
risk factor
Autism, susceptibility to, 20
Health Risk
RS1751075634
risk factor
Autism, susceptibility to, 20
Health Risk
RS1751123722
risk factor
Autism, susceptibility to, 20
Health Risk
All Variants (4)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS749776633 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, Autism, susceptibility to |
| RS1750373491 | Health Risk | risk factor | Autism, susceptibility to, 20 |
| RS1751075634 | Health Risk | risk factor | Autism, susceptibility to, 20 |
| RS1751123722 | Health Risk | risk factor | Autism, susceptibility to, 20 |