NCOA6 Chromosome 20
Nuclear receptor coactivator 6
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What This Gene Does
The protein encoded by this gene is a transcriptional coactivator that can interact with nuclear hormone receptors to enhance their transcriptional activator functions. This protein has been shown to be involved in the hormone-dependent coactivation of several receptors, including prostanoid, retinoid, vitamin D3, thyroid hormone, and steroid receptors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011]
Key Variants
All Variants (2)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS61730987 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS758456559 | Health Risk | Conflicting classifications of pathogenicity | — |