NANOS1 Chromosome 10
Nanos C2HC-type zinc finger 1
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What This Gene Does
This gene encodes a CCHC-type zinc finger protein that is a member of the nanos family. This protein co-localizes with the RNA-binding protein pumilio RNA-binding family member 2 and may be involved in regulating translation as a post-transcriptional repressor. Mutations in this gene are associated with spermatogenic impairment. [provided by RefSeq, Sep 2015]
Gene Info
Gene Group
Zinc fingers Nanos C2HC-type
Locus Type
gene with protein product
Location
10q26.11
Ensembl
ENSG00000188613
Associated Conditions (1)
Spermatogenic failure 12
Key Variants
All Variants (2)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS757643633 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS538539239 | Health Risk | Pathogenic | Spermatogenic failure 12, Spermatogenic failure 12 |