LY6G5B Chromosome 6
Lymphocyte antigen 6 family member G5B
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What This Gene Does
LY6G5B belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction (Mallya et al., 2002 [PubMed 12079290]).[supplied by OMIM, Mar 2008]
Gene Info
Gene Group
LY6/PLAUR domain containing
Locus Type
gene with protein product
Location
6p21.33
Ensembl
ENSG00000240053
Associated Conditions (1)
Poirier-Bienvenu neurodevelopmental syndrome
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS2536958296 | Health Risk | Likely pathogenic | Poirier-Bienvenu neurodevelopmental syndrome, Poirier-Bienvenu neurodevelopmental syndrome |