KLLN Chromosome 10
Killin, p53 regulated DNA replication inhibitor
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What This Gene Does
The protein encoded by this intronless gene is found in the nucleus, where it can inhibit DNA synthesis and promote S phase arrest coupled to apoptosis. The expression of this DNA binding protein is upregulated by transcription factor p53. [provided by RefSeq, Dec 2012]
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS899815496 | Health Risk | Conflicting classifications of pathogenicity | — |