KIF26A Chromosome 14
Kinesin family member 26A
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What This Gene Does
Predicted to enable microtubule binding activity. Involved in cerebral cortex development; regulation of neuron migration; and regulation of neuron projection development. Predicted to be located in cytosol. Implicated in complex cortical dysplasia with other brain malformations. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
Kinesins
Locus Type
gene with protein product
Location
14q32.33
Ensembl
ENSG00000066735
Associated Conditions (3)
Cortical dysplasia
complex
with other brain malformations 11
Key Variants
RS200958438
Conflicting classifications of pathogenicity
Cortical dysplasia, complex, with other brain malformations 11
Health Risk
RS2511491044
Likely pathogenic
Cortical dysplasia, complex, with other brain malformations 11
Health Risk
RS2511493694
Likely pathogenic
Cortical dysplasia, complex, with other brain malformations 11
Health Risk
RS1003059932
Pathogenic
Cortical dysplasia, complex, with other brain malformations 11
Health Risk
RS2511492071
Pathogenic
Cortical dysplasia, complex, with other brain malformations 11
Health Risk
RS746572271
Pathogenic
Cortical dysplasia, complex, with other brain malformations 11
Health Risk
RS771825279
Pathogenic
Cortical dysplasia, complex, with other brain malformations 11
Health Risk
RS776136395
Pathogenic
Cortical dysplasia, complex, with other brain malformations 11
Health Risk
All Variants (8)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS200958438 | Health Risk | Conflicting classifications of pathogenicity | Cortical dysplasia, complex, with other brain malformations 11 |
| RS2511491044 | Health Risk | Likely pathogenic | Cortical dysplasia, complex, with other brain malformations 11 |
| RS2511493694 | Health Risk | Likely pathogenic | Cortical dysplasia, complex, with other brain malformations 11 |
| RS1003059932 | Health Risk | Pathogenic | Cortical dysplasia, complex, with other brain malformations 11 |
| RS2511492071 | Health Risk | Pathogenic | Cortical dysplasia, complex, with other brain malformations 11 |
| RS746572271 | Health Risk | Pathogenic | Cortical dysplasia, complex, with other brain malformations 11 |
| RS771825279 | Health Risk | Pathogenic | Cortical dysplasia, complex, with other brain malformations 11 |
| RS776136395 | Health Risk | Pathogenic | Cortical dysplasia, complex, with other brain malformations 11 |