JUN Chromosome 1
Jun proto-oncogene, AP-1 transcription factor subunit
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What This Gene Does
This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq, Jul 2008]
Gene Info
Gene Group
"Basic leucine zipper proteins|Jun transcription factor family"
Locus Type
gene with protein product
Location
1p32.1
Ensembl
ENSG00000177606
Associated Conditions (1)
Breast neoplasm
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS2524557470 | Health Risk | Pathogenic | Breast neoplasm, Breast neoplasm |