INAVA Chromosome 1

Innate immunity activator

1 variant 1 Health Risk

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What This Gene Does

Involved in several processes, including nucleotide-binding activity oligomerization domain containing 2 signaling pathway; positive regulation of cytokine production; and positive regulation of intracellular signal transduction. Located in cytoplasm and nuclear body. Implicated in inflammatory bowel disease 29. [provided by Alliance of Genome Resources, Jul 2025]

Associated Conditions (1)

Inflammatory bowel disease 29

Key Variants

RS41313912

Conflicting classifications of pathogenicity

Inflammatory bowel disease 29, Inflammatory bowel disease 29

Health Risk

All Variants (1)

RSID	Category	Clinical Significance	Conditions
RS41313912	Health Risk	Conflicting classifications of pathogenicity	Inflammatory bowel disease 29, Inflammatory bowel disease 29