IL23R Chromosome 1
Interleukin 23 receptor
Upload your DNA to see your personal genotypes for variants in IL23R.
What This Gene Does
The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. [provided by RefSeq, Jul 2008]
Key Variants
All Variants (4)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS1442474244 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS2102637431 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS758022455 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS767104591 | Health Risk | Conflicting classifications of pathogenicity | — |