IL22RA2 Chromosome 6
Interleukin 22 receptor subunit alpha 2
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What This Gene Does
This gene encodes a member of the class II cytokine receptor family. The encoded soluble protein specifically binds to and inhibits interleukin 22 activity by blocking the interaction of interleukin 22 with its cell surface receptor. The encoded protein may be important in the regulation of inflammatory response, and has been implicated in the regulation of tumorigenesis in the colon. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013]
Gene Info
Gene Group
Interleukin receptors
Locus Type
gene with protein product
Location
6q23.3
Ensembl
ENSG00000164485
Associated Conditions (1)
Multisystem inflammatory syndrome in children
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS201560036 | Health Risk | risk factor | Multisystem inflammatory syndrome in children, Multisystem inflammatory syndrome in children |