ICAM1 Chromosome 19

Intercellular adhesion molecule 1

2 variants 2 Health Risk

Upload your DNA to see your personal genotypes for variants in ICAM1.

What This Gene Does

This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008]

Gene Info

Gene Group

"CD molecules|Receptor ligands|Immunoglobulin like domain containing|Ig-like cell adhesion molecule family"

Locus Type

gene with protein product

Location

19p13.2

Ensembl

ENSG00000090339

Associated Conditions (4)

Malaria

cerebral

susceptibility to

ICAM1-related disorder

Key Variants

RS5491

Benign; risk factor

Malaria, cerebral, susceptibility to

Health Risk

RS5030400

Conflicting classifications of pathogenicity

Malaria, susceptibility to, Malaria

Health Risk

All Variants (2)

RSID	Category	Clinical Significance	Conditions
RS5491	Health Risk	Benign; risk factor	Malaria, cerebral, susceptibility to
RS5030400	Health Risk	Conflicting classifications of pathogenicity	Malaria, susceptibility to, Malaria