HTR3B Chromosome 11
5-hydroxytryptamine receptor 3B
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What This Gene Does
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It is not functional as a homomeric complex, but a pentaheteromeric complex with subunit A (HTR3A) displays the full functional features of this receptor. [provided by RefSeq, Aug 2011]
Gene Info
Gene Group
5-hydroxytryptamine receptors, ionotropic
Locus Type
gene with protein product
Location
11q23.2
Ensembl
ENSG00000149305
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS145278314 | Health Risk | Conflicting classifications of pathogenicity | — |