GTSF1 Chromosome 12
Gametocyte specific factor 1
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What This Gene Does
Enables tRNA binding activity. Predicted to be involved in piRNA-mediated gene silencing by mRNA destabilization and secondary piRNA processing. Predicted to be located in cytoplasm. Predicted to be active in piP-body. [provided by Alliance of Genome Resources, Apr 2025]
Gene Info
Gene Group
Zinc fingers U11-48K-like CHHC-type
Locus Type
gene with protein product
Location
12q13.13
Ensembl
ENSG00000170627
Associated Conditions (1)
Male infertility
Key Variants
All Variants (2)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS761767389 | Health Risk | Likely pathogenic | Male infertility, Male infertility |
| RS2498504999 | Health Risk | Pathogenic | Male infertility, Male infertility |