GTSF1 Chromosome 12

Gametocyte specific factor 1
2 variants 2 Health Risk

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What This Gene Does
Enables tRNA binding activity. Predicted to be involved in piRNA-mediated gene silencing by mRNA destabilization and secondary piRNA processing. Predicted to be located in cytoplasm. Predicted to be active in piP-body. [provided by Alliance of Genome Resources, Apr 2025]
Gene Info
Gene Group
Zinc fingers U11-48K-like CHHC-type
Locus Type
gene with protein product
Location
12q13.13
Ensembl
ENSG00000170627
Associated Conditions (1)
Male infertility
Key Variants
All Variants (2)
RSID Category Clinical Significance Conditions
RS761767389 Health Risk Likely pathogenic Male infertility, Male infertility
RS2498504999 Health Risk Pathogenic Male infertility, Male infertility
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