GPR50 Chromosome X
G protein-coupled receptor 50
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What This Gene Does
This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women. [provided by RefSeq, Jan 2010]
Gene Info
Gene Group
G protein-coupled receptors, Class A orphans
Locus Type
gene with protein product
Location
Xq28
Ensembl
ENSG00000102195
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS765982317 | Health Risk | Conflicting classifications of pathogenicity | — |