GPR101 Chromosome X
G protein-coupled receptor 101
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What This Gene Does
The protein encoded by this gene is an orphan G protein-coupled receptor of unknown function. The encoded protein is a member of a family of proteins that contain seven transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. [provided by RefSeq, Sep 2011]
Gene Info
Gene Group
G protein-coupled receptors, Class A orphans
Locus Type
gene with protein product
Location
Xq26.3
Ensembl
ENSG00000165370
Associated Conditions (4)
GPR101-related disorder
Pituitary adenoma
growth hormone-secreting
2
Key Variants
RS140785131
Conflicting classifications of pathogenicity
GPR101-related disorder, GPR101-related disorder
Health Risk
RS149334737
Conflicting classifications of pathogenicity
Health Risk
RS73637412
Conflicting classifications of pathogenicity
Pituitary adenoma, growth hormone-secreting, 2
Health Risk
RS766636946
Conflicting classifications of pathogenicity
Health Risk
RS1556379508
Pathogenic
Pituitary adenoma, growth hormone-secreting, 2
Health Risk
All Variants (5)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS140785131 | Health Risk | Conflicting classifications of pathogenicity | GPR101-related disorder, GPR101-related disorder |
| RS149334737 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS73637412 | Health Risk | Conflicting classifications of pathogenicity | Pituitary adenoma, growth hormone-secreting, 2 |
| RS766636946 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS1556379508 | Health Risk | Pathogenic | Pituitary adenoma, growth hormone-secreting, 2 |