GIT1 Chromosome 17

GIT ArfGAP 1
1 variant 1 Health Risk

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What This Gene Does
Enables gamma-tubulin binding activity. Involved in positive regulation of microtubule nucleation and regulation of cytokinesis. Located in several cellular components, including focal adhesion; microtubule cytoskeleton; and mitochondrion. Implicated in attention deficit hyperactivity disorder. Biomarker of Huntington's disease. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
"ArfGAPs|Ankyrin repeat domain containing"
Locus Type
gene with protein product
Location
17q11.2
Ensembl
ENSG00000108262
Associated Conditions (1)
Inborn genetic diseases
Key Variants
All Variants (1)
RSID Category Clinical Significance Conditions
RS150427746 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
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