GBP2 Chromosome 1
Guanylate binding protein 2
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What This Gene Does
This gene belongs to the guanine-binding protein (GBP) family, which includes interferon-induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP). The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas. [provided by RefSeq, Jul 2013]
Gene Info
Gene Group
Guanylate binding proteins
Locus Type
gene with protein product
Location
1p22.2
Ensembl
ENSG00000162645
Associated Conditions (1)
Inherited susceptibility to mycobacterial diseases
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS753229736 | Health Risk | Likely risk allele | Inherited susceptibility to mycobacterial diseases, Inherited susceptibility to mycobacterial diseases |