FLRT1 Chromosome 11
Fibronectin leucine rich transmembrane protein 1
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What This Gene Does
This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. The family members may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. The encoded protein shares sequence similarity with two other family members, FLRT2 and FLRT3. This gene is expressed in kidney and brain. [provided by RefSeq, Jul 2008]
Gene Info
Gene Group
Fibronectin type III domain containing
Locus Type
gene with protein product
Location
11q13.1
Ensembl
ENSG00000126500
Associated Conditions (2)
Peripheral neuropathy
FLRT1-related disorder
Key Variants
All Variants (2)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS143337663 | Health Risk | Conflicting classifications of pathogenicity | Peripheral neuropathy, FLRT1-related disorder, Peripheral neuropathy |
| RS79628679 | Health Risk | Conflicting classifications of pathogenicity | Peripheral neuropathy, Peripheral neuropathy |