FGD6 Chromosome 12
FYVE, RhoGEF and PH domain containing 6
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What This Gene Does
Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in actin cytoskeleton organization; filopodium assembly; and regulation of cell shape. Predicted to be located in Golgi apparatus; lamellipodium; and ruffle. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
"Zinc fingers FYVE-type|Pleckstrin homology domain containing|Dbl family Rho GEFs"
Locus Type
gene with protein product
Location
12q22
Ensembl
ENSG00000180263
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS141232857 | Health Risk | Conflicting classifications of pathogenicity | — |