EP400 Chromosome 12
E1A binding protein p400
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What This Gene Does
Predicted to enable chromatin binding activity. Involved in positive regulation of double-strand break repair via homologous recombination and regulation of cell cycle. Part of NuA4 histone acetyltransferase complex; Swr1 complex; and nucleosome. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
"Myb/SANT domain containing|SNF2 related family|Tip60/Nua4 histone acetyltransferase complex subunits|Small nucleolar RNA protein coding host genes"
Locus Type
gene with protein product
Location
12q24.33
Ensembl
ENSG00000183495
Key Variants
All Variants (4)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS143981004 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS144245663 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS541534183 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS771703326 | Health Risk | Conflicting classifications of pathogenicity | — |