ELMO2 Chromosome 20

Engulfment and cell motility 2
6 variants 6 Health Risk

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What This Gene Does
The protein encoded by this gene interacts with the dedicator of cyto-kinesis 1 protein. Similarity to a C. elegans protein suggests that this protein may function in phagocytosis of apoptotic cells and in cell migration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Info
Gene Group
Engulfment and cell motility proteins
Locus Type
gene with protein product
Location
20q13.12
Ensembl
ENSG00000062598
Associated Conditions (1)
Primary intraosseous venous malformation
Key Variants
All Variants (6)
RSID Category Clinical Significance Conditions
RS1372506599 Health Risk Likely pathogenic Primary intraosseous venous malformation, Primary intraosseous venous malformation
RS1568748859 Health Risk Likely pathogenic Primary intraosseous venous malformation, Primary intraosseous venous malformation
RS886037918 Health Risk Likely pathogenic Primary intraosseous venous malformation, Primary intraosseous venous malformation
RS2145827538 Health Risk Pathogenic Primary intraosseous venous malformation, Primary intraosseous venous malformation
RS768410753 Health Risk Pathogenic Primary intraosseous venous malformation, Primary intraosseous venous malformation, Primary intraosseous venous malformation
RS886037919 Health Risk Pathogenic Primary intraosseous venous malformation, Primary intraosseous venous malformation
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