DPY19L2 Chromosome 12

Dpy-19 like 2
6 variants 6 Health Risk

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What This Gene Does
The protein encoded by this gene belongs to the dpy-19 family. It is highly expressed in testis, and is required for sperm head elongation and acrosome formation during spermatogenesis. Mutations in this gene are associated with an infertility disorder, spermatogenic failure type 9 (SPGF9). [provided by RefSeq, Dec 2011]
Associated Conditions (4)
Spermatogenic failure 9
Thyroid cancer
nonmedullary
1
Key Variants
All Variants (6)
RSID Category Clinical Significance Conditions
RS147579680 Health Risk Pathogenic Spermatogenic failure 9, Thyroid cancer, nonmedullary
RS587777205 Health Risk Pathogenic Spermatogenic failure 9, Spermatogenic failure 9
RS587777206 Health Risk Pathogenic Spermatogenic failure 9, Spermatogenic failure 9
RS751879424 Health Risk Pathogenic Spermatogenic failure 9, Spermatogenic failure 9
RS752764341 Health Risk Pathogenic Spermatogenic failure 9, Spermatogenic failure 9
RS868256749 Health Risk Pathogenic Spermatogenic failure 9, Spermatogenic failure 9
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