DNAH17 Chromosome 17
Dynein axonemal heavy chain 17
Upload your DNA to see your personal genotypes for variants in DNAH17.
What This Gene Does
Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. DNAH17 is a heavy chain associated with axonemal dynein (Milisav and Affara, 1998 [PubMed 9545504]).[supplied by OMIM, Mar 2008]
Gene Info
Gene Group
Dyneins, axonemal outer arm complex subunits
Locus Type
gene with protein product
Location
17q25.3
Ensembl
ENSG00000187775
Associated Conditions (5)
Inborn genetic diseases
DNAH17-related disorder
Spermatogenic failure 39
Short stature
Male infertility with spermatogenesis disorder
Key Variants
RS113616418
Conflicting classifications of pathogenicity
Inborn genetic diseases, DNAH17-related disorder, Inborn genetic diseases
Health Risk
RS143872440
Conflicting classifications of pathogenicity
DNAH17-related disorder, Inborn genetic diseases, DNAH17-related disorder
Health Risk
RS144732617
Conflicting classifications of pathogenicity
Inborn genetic diseases, DNAH17-related disorder, Inborn genetic diseases
Health Risk
RS145458355
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS145505271
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS200203879
Conflicting classifications of pathogenicity
Inborn genetic diseases, DNAH17-related disorder, Inborn genetic diseases
Health Risk
RS201593974
Conflicting classifications of pathogenicity
Inborn genetic diseases, DNAH17-related disorder, Inborn genetic diseases
Health Risk
RS202169863
Conflicting classifications of pathogenicity
Inborn genetic diseases, DNAH17-related disorder, Inborn genetic diseases
Health Risk
RS372755956
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS375620938
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS59690629
Conflicting classifications of pathogenicity
Inborn genetic diseases, DNAH17-related disorder, Inborn genetic diseases
Health Risk
RS76449350
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
All Variants (27)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS113616418 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, DNAH17-related disorder, Inborn genetic diseases |
| RS143872440 | Health Risk | Conflicting classifications of pathogenicity | DNAH17-related disorder, Inborn genetic diseases, DNAH17-related disorder |
| RS144732617 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, DNAH17-related disorder, Inborn genetic diseases |
| RS145458355 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, Inborn genetic diseases |
| RS145505271 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, Inborn genetic diseases |
| RS200203879 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, DNAH17-related disorder, Inborn genetic diseases |
| RS201593974 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, DNAH17-related disorder, Inborn genetic diseases |
| RS202169863 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, DNAH17-related disorder, Inborn genetic diseases |
| RS372755956 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, Inborn genetic diseases |
| RS375620938 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, Inborn genetic diseases |
| RS59690629 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, DNAH17-related disorder, Inborn genetic diseases |
| RS76449350 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, Inborn genetic diseases |
| RS201018927 | Health Risk | Likely pathogenic | Spermatogenic failure 39, Spermatogenic failure 39 |
| RS2086970259 | Health Risk | Likely pathogenic | DNAH17-related disorder, DNAH17-related disorder |
| RS2511477180 | Health Risk | Likely pathogenic | DNAH17-related disorder, DNAH17-related disorder |
| RS2511560242 | Health Risk | Likely pathogenic | Spermatogenic failure 39, Spermatogenic failure 39 |
| RS745525261 | Health Risk | Likely pathogenic | DNAH17-related disorder, DNAH17-related disorder |
| RS748912987 | Health Risk | Likely pathogenic | DNAH17-related disorder, DNAH17-related disorder |
| RS757601640 | Health Risk | Likely pathogenic | DNAH17-related disorder, DNAH17-related disorder |
| RS763505389 | Health Risk | Likely pathogenic | Short stature, Short stature |
| RS768564744 | Health Risk | Likely pathogenic | Short stature, Short stature |
| RS769976401 | Health Risk | Likely pathogenic | Male infertility with spermatogenesis disorder, Male infertility with spermatogenesis disorder |
| RS1598525781 | Health Risk | Pathogenic | Spermatogenic failure 39, Spermatogenic failure 39 |
| RS1598595659 | Health Risk | Pathogenic | Spermatogenic failure 39, Spermatogenic failure 39 |
| RS2146716548 | Health Risk | Pathogenic | Spermatogenic failure 39, Spermatogenic failure 39 |
| RS767723684 | Health Risk | Pathogenic | Spermatogenic failure 39, Spermatogenic failure 39 |
| RS775503600 | Health Risk | Pathogenic | Spermatogenic failure 39, Spermatogenic failure 39 |