DGAT2 Chromosome 11

Diacylglycerol O-acyltransferase 2
4 variants 4 Health Risk

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What This Gene Does
This gene encodes one of two enzymes which catalyzes the final reaction in the synthesis of triglycerides in which diacylglycerol is covalently bound to long chain fatty acyl-CoAs. The encoded protein catalyzes this reaction at low concentrations of magnesium chloride while the other enzyme has high activity at high concentrations of magnesium chloride. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Info
Gene Group
Diacylglycerol O-acyltransferase 2 family
Locus Type
gene with protein product
Location
11q13.5
Ensembl
ENSG00000062282
Key Variants
All Variants (4)
RSID Category Clinical Significance Conditions
RS138423103 Health Risk Conflicting classifications of pathogenicity
RS150303834 Health Risk Conflicting classifications of pathogenicity
RS151179593 Health Risk Conflicting classifications of pathogenicity
RS774044430 Health Risk Conflicting classifications of pathogenicity
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