CSDE1 Chromosome 1
Cold shock domain containing E1
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What This Gene Does
Enables RISC complex binding activity; RNA stem-loop binding activity; and lncRNA binding activity. Involved in IRES-dependent viral translational initiation; regulation of gene expression; and stress granule assembly. Located in Golgi apparatus; cytosol; and plasma membrane. Part of CRD-mediated mRNA stability complex and mCRD-mediated mRNA stability complex. [provided by Alliance of Genome Resources, Jul 2025]
Associated Conditions (1)
CSDE1-associated disorder
Key Variants
RS1659401492
Likely pathogenic
CSDE1-associated disorder, CSDE1-associated disorder
Health Risk
RS2524846674
Likely pathogenic
Health Risk
RS1051649561
Pathogenic
Health Risk
RS1466129760
Pathogenic
Health Risk
RS2101005817
Pathogenic
Health Risk
RS2101056946
Pathogenic
Health Risk
RS2524847177
Pathogenic
Health Risk
All Variants (7)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS1659401492 | Health Risk | Likely pathogenic | CSDE1-associated disorder, CSDE1-associated disorder |
| RS2524846674 | Health Risk | Likely pathogenic | — |
| RS1051649561 | Health Risk | Pathogenic | — |
| RS1466129760 | Health Risk | Pathogenic | — |
| RS2101005817 | Health Risk | Pathogenic | — |
| RS2101056946 | Health Risk | Pathogenic | — |
| RS2524847177 | Health Risk | Pathogenic | — |