CGAS Chromosome 6
Cyclic GMP-AMP synthase
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What This Gene Does
Enables several functions, including 2',3'-cyclic GMP-AMP synthase activity; molecular condensate scaffold activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in several processes, including intracellular signal transduction; paracrine signaling; and regulation of defense response. Located in nuclear body; plasma membrane; and site of double-strand break. Is active in cytosol and nucleus. [provided by Alliance of Genome Resources, Jul 2025]
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS147035222 | Health Risk | Conflicting classifications of pathogenicity | — |