CD244 Chromosome 1
CD244 molecule
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What This Gene Does
This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
Gene Info
Gene Group
"CD molecules|Immunoglobulin like domain containing|Ig-like cell adhesion molecule family"
Locus Type
gene with protein product
Location
1q23.3
Ensembl
ENSG00000122223
Associated Conditions (1)
Rheumatoid arthritis
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS3766379 | Health Risk | risk factor | Rheumatoid arthritis, Rheumatoid arthritis |